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  • Chronic Wound Management : The Significance of Evidence and Technology
    Chronic Wound Management : The Significance of Evidence and Technology

    This book describes how chronic wounds follow a completely different healing trajectory to acute wounds and discusses the factors associated with these poor healing trajectories. These factors include age, chronic inflammation, phenotypic changes in such cells as macrophages, fibroblasts, and keratinocytes, colder, alkaline wound milieu, wound related hypoxemia, and diabetes. Other factors implicated include reperfusion injury, poor patient compliance, presence of undiagnosed and therefore unmanaged biofilms and wound pain.The past decades have yielded reliable evidence-based guidelines and standardized care, but the healing of diabetic foot wounds continues to be unpredictable notwithstanding these advances, while the recurrence rates are also high. The benefits of technology in wound diagnosis are evidence-based and the use of this technology also features in guidelines.  However, the same argument cannot be extended to adjuvant devices to facilitate wound closure even though many devices potentially benefit wound healing.  Chronic Wound Management describes how innovation is based on technology that itself informs evidence, the gap between the evidence available, the performance of technology and how do we bridge this gap. It reviews the lessons learnt from the COVID-19 pandemic and whether traditional medicine systems offer us real or imaginary benefits. Consequently, this book is an important addition to the literature in the area and an essential read for all healthcare professionals working with these patients.

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  • Days of Significance
    Days of Significance

    Written in response to Much Ado About Nothing and performed by Dominic Cooke's Pericles and The Winter's Tale Company, Roy Williams' Days of Significance is set in market-town England and the deserts of Iraq.Two young soldiers join their friends to binge drink the night before they leave for active service.Their complex love lives and mortal fears directly impact on their tour of duty.Roy Williams looks at how the naive and malformed moral codes of these young men have catastrophic reverberations for the West's moral authority.

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  • The Significance of Dreams : Bridging Clinical and Extraclinical Research in Psychoanalysis
    The Significance of Dreams : Bridging Clinical and Extraclinical Research in Psychoanalysis

    This book looks at dreams from a twenty-first century perspective.It takes its inspiration from Freud's insights, but pursues psychoanalytic interest into both neuroscience and the modern psychoanalytic consulting room.The book looks at laboratory research on dreaming alongside the modern clinical use of dreams and links together clinical and empirical research, integrating classical ideas with the plurality of psychoanalytic theoretical constructs available to modern researchers.Psychoanalysts writing about dreams have traditionally represented the cutting edge of clinical and theoretical development, and this book is no exception.Many of the contributions, as well as the epistemological position taken by the writers, represent a kind of radical openness to new ways of thinking about the clinical situation and about theory.In line with the ambition of the editors, this volume represents an integration of theories and disciplines, and a scientific context for modern psychoanalysis.The link between clinical research and extraclinical research via the royal road of dreaming is a theme that runs through all the contributions.These cover dreaming as it sheds light on clinical conditions such as depression and trauma, or dreams as they form a core aspect of clinical work; be that as a co-construction, or as shared play between therapist and patients.The book provides insight through dreams to understanding mental functions in all clinical situations and across all conditions.

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  • The Song of Significance
    The Song of Significance

    "Humans aren't a resource to be bought, used and discarded - they are the point of the workplace, the life essence of innovation, growth and success."From the bestselling author of Purple Cow and This Is Marketing comes an urgent manifesto for leaders facing unprecedented challenges in a rapidly-changing workplace. The workplace has undergone a massive shift. Remote work and economic instability have depressed innovation and left us disconnected and disengaged.Paychecks no longer buy loyalty, happiness, and effort.Quiet quitting runs rampant, and people show up without truly showing up.Alarmed managers are doubling down on keystroke surveillance, productivity tracking and back-to-the-office mandates, when what they should be doing is the opposite - affording employees the dignity necessary to inject purpose and motivation into their work. In The Song of Significance, legendary author and business thinker Seth Godin posits a new view of what industry leaders must do now.If you want your employees to live up to their full professional potential, you must give them the respect and autonomy they deserve as humans.The choice is simple: either keep treating your people as disposable and join in the AI-fueled race to the bottom, or build a significant organization that enrolls, empowers, and trusts employees to deliver their best work, no matter where they're working.

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  • What significance do constellations have for science?

    Constellations have significance for science as they provide a way for astronomers to organize and locate stars in the night sky. By identifying and mapping out constellations, scientists can better understand the positions and movements of stars, as well as study their characteristics and behavior. This knowledge is crucial for advancing our understanding of the universe and for making important astronomical discoveries. Additionally, constellations have played a historical role in navigation and timekeeping, making them important for both scientific and practical purposes.

  • What significance do the constellations have for science?

    Constellations have significant importance in science as they help astronomers locate and identify celestial objects in the night sky. By mapping out the positions of constellations, scientists can navigate the vastness of space and study the movements of stars and planets. Additionally, constellations provide a framework for organizing and categorizing stars, aiding in the understanding of stellar evolution and the structure of the universe. Overall, constellations play a crucial role in advancing our knowledge of astronomy and the cosmos.

  • What is the significance of science for industrialization?

    Science plays a crucial role in industrialization by driving innovation and technological advancements. Through scientific research and development, new technologies and processes are created, leading to increased efficiency and productivity in industrial operations. This, in turn, contributes to economic growth and the creation of new industries and job opportunities. Additionally, scientific advancements in fields such as materials science, chemistry, and engineering have led to the development of new materials, products, and manufacturing techniques, further fueling industrialization. Overall, science is essential for driving the progress and success of industrialization.

  • What is the significance of emotional development for practice?

    Emotional development is significant for practice because it impacts how individuals interact with others, manage stress, and make decisions. In a practice setting, emotional development can influence how clients respond to interventions and how practitioners build rapport and trust with them. Understanding emotional development can also help practitioners recognize and address underlying emotional issues that may be contributing to a client's presenting concerns. Additionally, emotional development is important for practitioners to manage their own emotions and maintain professional boundaries in their work with clients.

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  • The Significance of Swans
    The Significance of Swans


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  • Science, Technology And Innovation Indicators : Lessons from the Development Experience in Africa
    Science, Technology And Innovation Indicators : Lessons from the Development Experience in Africa


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  • Matters of Significance : Replication, Translation and Academic Freedom in Developmental Science
    Matters of Significance : Replication, Translation and Academic Freedom in Developmental Science


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  • Jackson Pollack : Meaning And Significance
    Jackson Pollack : Meaning And Significance

    Designed to help students and interested general readers to interpret the abstract expressionist paintings of Jackson Pollock, this survey of Pollock's life and art provides insight into the origins and meanings of individual works and analyzes the influences upon Pollock.Also included are discussions of the many issues raised by Pollock's work above and beyond his intentions, and how they intersected with the work of his contemporaries as well as other intellectual currents of the time.

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  • What is the significance of temperature in electrical engineering?

    Temperature is a critical factor in electrical engineering as it directly affects the performance and lifespan of electronic components. High temperatures can lead to increased resistance in conductors, causing overheating and potential damage to the circuit. Additionally, temperature variations can impact the accuracy and stability of electronic devices, such as sensors and transducers. Therefore, understanding and managing temperature is essential in designing reliable and efficient electrical systems.

  • What is the significance of a specialist in metal technology?

    A specialist in metal technology plays a crucial role in various industries such as manufacturing, construction, and engineering. They possess the expertise and skills needed to work with different types of metals, understand their properties, and utilize various techniques to shape and manipulate them. Their knowledge helps in creating high-quality metal products, ensuring structural integrity, and meeting industry standards. Overall, specialists in metal technology contribute to the advancement of technology and innovation in various sectors.

  • What is the significance of laboratory mice in cancer research?

    Laboratory mice are significant in cancer research because they share genetic and biological similarities with humans, making them valuable models for studying cancer. Researchers can use mice to study the development and progression of cancer, test potential treatments, and understand the underlying mechanisms of the disease. Mice also allow for controlled experiments and the ability to manipulate their genetics to better understand the role of specific genes in cancer. Ultimately, the use of laboratory mice in cancer research has led to important discoveries and advancements in our understanding and treatment of cancer.

  • What is the significance of tourism as a factor for development?

    Tourism is significant for development as it can contribute to economic growth, job creation, and infrastructure development in a region. It can also help in preserving and promoting local culture and heritage, as well as fostering international understanding and cooperation. Additionally, tourism can generate foreign exchange earnings and investment in the local economy, leading to overall improvement in the standard of living for the local population. Therefore, tourism can play a crucial role in the sustainable development of a region.

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